ALS, hypermetabolism and diet

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Patients with amyotrophic lateral sclerosis (ALS) experience progressive limb weakness, muscle atrophy, and dysphagia, making them vulnerable to insufficient energy intake. Half of ALS patients suffer from hyper-metabolism.

In 2014 Edward J Kasarskis and his colleagues developed equations to estimate energy requirements of ALS patients.

They enrolled 80 ALS participants at varying stages of their illness, then developed statistical models to estimate TDEE by using factors easily obtained during a routine clinical visit.

Their predictive equations can serve as a basis for recommending placement of a feeding gastrostomy in ALS patients who fail to meet their energy requirements by oral intake.

They developed a Web-based calculator, but it seems to not work anymore.

I tried to replicate this calculator.

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